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Brian C. Zhang
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2025-12-28 23:44:55
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Brian C. Zhang- PhD Brian C. Zhang PhD, University of Oxford zhang.brian@gmail.com | [blog] I defended my PhD in 2022 and am now working as a computational biologist at Adaptive Biotechnologies! At Oxford, I was a member of Pier Palamara’s group . We developed a method, ARG-Needle, to infer the genome-wide genealogy of a set of genetic samples from genotyping array or sequencing data. We built the genome-wide genealogy of 337K samples in the UK Biobank and scanned the genealogy for associations with 7 complex traits. This yielded more rare and ultra-rare associations than found by genotype imputation, which were overall enriched for loss-of-function variation. See our paper in Nature Genetics or my thesis . During my PhD, I was supported by the Clarendon Scholarship and was a member of St. John’s College. Before Oxford, I worked for two years as a research engineer at DeepMind in London. Interests. Statistical Genetics, Population Genetics, Machine Learni...
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