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DRUSE | Druse DRUSE Skip to content Home About ← Older posts December 9, 2017 · 7:46 pm The diagnosis of young-onset dementia “Dementia is a major public health concern that is a growing burden owing to an ageing society. However, the high prevalence of dementia in the elderly can overshadow the importance of its occurrence in younger patients. Young-onset dementias can present a substantial diagnostic challenge but can also provide important biological insights that might also be applicable to the more common presentation in older patients. For example, the high prevalence of inherited dementias in younger age-groups has led to the identification of causative genes and subsequent molecular pathology of direct relevance to the more common sporadic disease seen in older patients. The prospect of future treatments targeted at the specific molecular pathological changes of the different dementias makes precise diagnosis essential. In this Review, we discuss the differe...
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