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MetaSD - Don't just do something, stand there! Reflections on the counterintuitive behavior of complex systems, seen through the eyes of System Dynamics, Systems Thinking and simulation.
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Don't just do something, stand there! Reflections on the counterintuitive behavior of complex systems, seen through the eyes of System Dynamics, Systems Thinking and simulation.
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MetaSD - Don't just do something, stand there! Reflections on the counterintuitive behavior of complex systems, seen through the eyes of System Dynamics, Systems Thinking and simulation. Skip to content MetaSD Don't just do something, stand there! Reflections on the counterintuitive behavior of complex systems, seen through the eyes of System Dynamics, Systems Thinking and simulation. Menu Model Library About Thyroid Dynamics: Hyper Resurgence In my last thyroid post , I described a classic case of overshoot due to failure to account for delays. I forgot to mention the trigger for this episode. At point B above, there was a low TSH measurement, at .05 well below the recommended floor of .4. That was taken as a signal for a dose reduction, which is qualitatively reasonable. Let’s suppose we believe the dose-TSH response to be stable: Then we have some puzzles. First, at 200mcg, we’d expect TSH=.15, about 3x higher. To get the observed measurement, we’d expect the ...
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