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Open Graph

title

The Synthetic Referee

description

A Synthetic/Medicinal Chemistry Blog

image

site name

The Synthetic Referee

author

updated

2026-02-26 20:58:12

raw text

The Synthetic Referee | A Synthetic/Medicinal Chemistry Blog The Synthetic Referee A Synthetic/Medicinal Chemistry Blog Home About the Author Abstract jump to navigation CoMFA – MFer. March 8, 2007 Posted by thwalls in Blogroll . 5 comments  So I’m finishing up some of my work and of course a CoMFA is required since my work centers around the inhibition of a particular transmembrane protein.  Of course, if you’re familiar with medicinal chemistry, you’ll know that every medchem student is entrenched with the thorough understanding that if the computer tells you the analog is good, then obviously…it’s good.  This then leads to your PI telling you to make all 150,000 analogs that could possibly be good since, hey, the in vitro data may be different. I hate Sybyl, and I think it equally hates me.  And possibly you too. Happily Ever After March 8, 2007 Posted by thwalls in Synthetic Chemistry . 9 comments  You’ll have to excuse my prolonged hiatus fr...

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