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title
The Knowledge Traveler
description
vardhani.wordpress.com
site name
The Knowledge Traveler
author
updated
2026-02-25 05:41:03
raw text
The Knowledge Traveler | vardhani.wordpress.com The Knowledge Traveler vardhani.wordpress.com Home About Respon Imun terhadap Infeksi Virus Dengue (Patogenesis dan Patofisiologi DBD) 16 06 2010 Virus dengue termasuk ke dalam Arthropoda Borne Virus (Arbo virus) dan terdiri dari 4 s erotype yaitu DEN 1, 2, 3, dan 4. Infeksi virus dengue untuk pertama kali akan merangsang terbentuknya atibodi non-netralisasi. Sesuai dengan namanya, antibodi tersebut tidak bersifat menetralkan replikasi virus, tetapi justru memacu replikasi virus. Akibatnya terbentuk kompleks imun yang lebih banyak pada infeksi sekunder oleh serotype lain. Hal itu yang menyebabkan manifestasi klinis infeksi sekunder lebih berat dibanding infeksi sekunder (Soedarmo, 2002). Antibodi non-netralisasi yang terbentuk akan bersirkulasi bebas di darah atau menempel di sel fagosit mononuklear yang merupakan tempat utama infeksi virus dengue. Antibodi non-netralisasi yang menempel pada sel fagosit monon...
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