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The Bioinformatics for Combating Infectious Dieseases , or BCID, project is
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Bioinformatics for Combating Infectious Dieseases (BCID) Overview Infectious diseases are a leading cause of productivity loss and are responsible for roughly a third of annual deaths worldwide; sepsis and mortality caused by infectious diseases are also on the rise in the U.S. Antimicrobial resistance is increasing rapidly and newly emerging diseases are causing considerable concern: a new global pandemic could have a significant economic impact. With the advent of microbial whole-genome sequencing, there has been some renewed optimism that genomic knowledge will speed the development of new antimicrobials, vaccines and diagnostics. Some success stories have been reported to date, however these have been extensive/costly endeavors involving significant laboratory requirements. This is largely due to the fact that the existing computational screens for identifying potential drug targets and vaccine components are not accurate enough. We propose that throu...
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