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2026-02-24 01:20:56
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Jennifer's blog Jennifer's blog Previous Posts New Organic Chemistry III extra credit Archives June 2005 Friday, June 03, 2005 New Organic Chemistry III extra credit The following is the formation of a urea derivative (-NHCONH-), which is similar to the amide formation studied in Organic Chemistry III. This reaction is the last step in the synthesis of N-substituted 4-ureido-5,7-dichloro-quinolines (DCUKs), specifically DCUKA (N,N-(diphenyl)-4-ureido-5,7-dichloro-2-carboxy-quinoline), which is now being used in sedatives. Here is the reference for the above example. The following is the formation of an amide by performing the reaction of N’-(arylmethylene)- isonicotinohydrazides with pyrazine-2-carbonyl chloride in the presence of sodium hydride in toluene at reflux temperature. This is used in the formation of antimycobacterial agents. Here is the reference for the above example. posted by Miss Hillemann @ 9:44 AM 0 comments
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