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Organic Chemistry, Natural Products, Synthesis, Methodology
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site name
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2026-01-17 03:59:16
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Organic Chemistry, Natural Products, Synthesis, Methodology Home About Stereoselective Monofluoromethylation of Primary and Secondary Alcohols by Using a Fluorocarbon Nucleophile in a Mitsunobu Reaction Link: ACIEE EarlyView G. K. Surya Prakash * , Sujith Chacko, Steevens Alconcel, Timothy Stewart, Thomas Mathew, George A. Olah * Loker Hydrocarbon Research Institute and, Department of Chemistry, University of Southern California, University Park, Los Angeles, CA 90089-1661, USA The following method is very similar to this one , that it demonstrates a strategy to synthesize monofluoromethyl derivative compounds, at least in the purpose of the research. The products are different type as the one cited in the link above are amino fluoro methyl derivatives, but this one here, the method seems to be applicable to primary and secondary alcohols (via Mitsunobu), giving a wider variety of products. The reagent used in both papers is the same one, however ( 1 ). The initia...
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